发布日期:2023-07-07英文标题:NCCN Clinical Practice Guidelines in Oncology:B-Cell Lymphomas( Version 5.2023)制定者:
美国国家综合癌症网络
出处:NCCN官网摘要:
1.指南来源(Guide Source):
NCCN临床实践指南:B细胞淋巴瘤 V5.2023.发布已获NCCN肿瘤学临床实践指南(NCCN指南®)许可。©2022美国国家综合癌症网络公司.保留所有权利。未经NCCN明确的书面许可,不得出于任何目的以任何形式复制NCCN指南®和文中的插图。要查看NCCN指南的最新完整版本,请访问NCCN.org。NCCN指南是一项持续进行的工作,可能会随着新的重要数据的出现而不断完善。
2.免责声明(Disclaimers):
NCCN对其内容、使用或应用不做任何形式的担保,并否认以任何方式对其应用或使用承担任何责任。
在下载本篇指南前,请先您详细阅读并同意以下协议:
NCCN内容不得用于商业目的,以及NCCN作为NCCN内容的许可方,不作任何陈述或保证,并明确否认NCCN指南适用于任何特定患者的护理或治疗,任何医院、寻求使用《NCCN指南》治疗患者的临床医生或其他医疗服务提供者(“提供者”)应根据特定患者护理或治疗的具体临床情况做出独立的医疗判断,NCCN不建议、推荐或认可任何提供者(无论是否与被许可方相关)进行任何有偿或无偿的医疗治疗、咨询或服务,也不应因被许可方建议、推荐或认可任何此类提供者的作为或不作为而直接或间接承担责任。详见《NCCN最终用户许可协议》
3. 专家名单(Staff):
Andrew D. Zelenetz, MD, PhD/Chair † ÞMemorial Sloan Kettering Cancer Center
Leo I. Gordon, MD/Vice Chair ‡ ξRobert H. Lurie Comprehensive Cancer Center of Northwestern University
Jeremy S. Abramson, MD † ‡Massachusetts General Hospital Cancer Center
Ranjana H. Advani, MD † Stanford Cancer Institute
Nancy L. Bartlett, MD † Siteman Cancer Center at BarnesJewish Hospital and Washington University School of Medicine
L. Elizabeth Budde, MD, PhD † ξ City of Hope National Medical Center
Paolo F. Caimi, MD ‡ † Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
Julie E. Chang, MD ‡ University of Wisconsin Carbone Cancer Center
Beth Christian, MD † The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute
Sven De Vos, MD, PhD ‡ ÞUCLA Jonsson Comprehensive Cancer Center
Bhagirathbhai Dholaria, MD ‡ ξVanderbilt-Ingram Cancer Center
Bita Fakhri, MD † UCSF Helen Diller Family Comprehensive Cancer Center
Luis E. Fayad, MD ‡ Þ †The University of Texas MD Anderson Cancer Center
Thomas M. Habermann, MD ‡ ξMayo Clinic Cancer Center
Muhammad Saad Hamid, MD ‡ St. Jude Children's Research Hospital/The University of Tennessee Health Science Center
Francisco Hernandez-Ilizaliturri, MD † Roswell Park Comprehensive Cancer Center
Boyu Hu, MD † ‡ Þ Huntsman Cancer Institute at the University of Utah
Mark S. Kaminski, MD † University of Michigan Rogel Cancer Center
Christopher R. Kelsey, MD § Duke Cancer Institute
Nadia Khan, MD † Fox Chase Cancer Center
Rebecca King, MD ≠ Mayo Clinic Cancer Center
Susan Krivacic, MPAff ¥ Consultant
Ann S. LaCasce, MD † Dana-Farber/Brigham and Women’s Cancer Center
Megan Lim, MD, PhD ≠ Abramson Cancer Center at the University of Pennsylvania
Mayur Narkhede, MD † ‡ O'Neal Comprehensive Cancer Center at UAB
Rachel Rabinovitch, MD § University of Colorado Cancer Center
Praveen Ramakrishnan, MD, MS ‡ UT Southwestern Simmons Comprehensive Cancer Center
Erin Reid, MD ‡ UC San Diego Moores Cancer Center
Kenneth B. Roberts, MD § Yale Cancer Center/Smilow Cancer Hospital
Hayder Saeed, MD † ‡ Þ Moffitt Cancer Center
Stephen D. Smith, MD ‡ Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
Jakub Svoboda, MD ‡ Abramson Cancer Center at the University of Pennsylvania
Lode J. Swinnen, MB, ChB † ‡ ξ The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Joseph Tuscano, MD ‡ UC Davis Comprehensive Cancer Center
Julie M. Vose, MD, MBA ‡ ξ Fred & Pamela Buffett Cancer Center
4.临床试验(Clinical Trials):
NCCN认为任何癌症患者都可以在临床试验中得到最佳治疗,因此特别鼓励患者参与临床试验。 寻找NCCN成员组:https://www.nccn.org/home/member-institutions
5.NCCN对证据和共识分类( NCCN Categories of Evidence and Consensus):
推荐均为2A类,除非另有说明,请参见下表:
NCCN 对证据和共识的分类 | |
1类 | 基于高水平证据,NCCN一致认为此项治疗合理 |
2A类 | 基于低水平证据,NCCN一致认为此项治疗合理 |
2B类 | 基于低水平证据,NCCN基本认为此项治疗合理 |
3类 | 基于任何水平证据,NCCN对此项治疗是否合理存在重大分歧 |
6.NCCN首选分类( NCCN Categories of Preference):
所有建议均视为合理,请参见下表:
NCCN 优先使用分类 | |
首选干预方法 | 若合适,可负担,则基于疗效、安全性和证据更优的干预方法 |
推荐的其他干预方法 | 其他繁育方法可能疗效较低,毒性更多,或一句的数据不太成熟;或者具有相似疗效,但费用明显较高 |
某些情况下有用 | 其他干预方法可能会用于选定的患者人群(根据推荐类型定义) |